BREAKTHROUGH IN HEART HEALTH

April 2, 2015 at 8:24 pm Leave a comment

As many of you are aware, I had to close my Clinic in 2013 due to a sudden, acute illness. That illness was acute heart failure, triggered by a prescription medication I was given for a bleeding ulcer. I want to share with you the supplementation that brought me back to health.

I have treated heart failure for years. The problem in my case was that there was no diagnosis; all of the medical doctors thought I had cancer, since my tumor marker (CA-125) was elevated, and rising rapidly. I went to a cancer clinic in Tijuana, Oasis of Hope, which was an amazing experience. After running a full battery of tests, Dr. Contreras was the first to suggest that I didn’t have cancer; however, since they didn’t know what was wrong with me, they were “afraid not to treat me.” Those were his very words.

After returning home, I had another blood test, specific to cancer, through an international laboratory, Research Genetic Cancer Centre (RGCC). Originally established in Cyprus, the laboratory now operates internationally, with branch offices in the U.S., Central Europe, the United Kingdom and Hungary. They run amazing blood tests, specifically looking for circulating cancer cells, as well as cancer stem cells. Nothing was found in my sample. However, I was still ill and was still having trouble walking across a room without becoming severely breathless.

So, I undertook an online search, googling the phrase “CA-125 and heart symptoms.” I immediately hit pay dirt. It seems that in the early to mid-2000s, researchers discovered that, in acute heart failure, the ventricles secrete CA-125. Furthermore, there was a second test called B.N.P. (B-type natriuretic peptide), a substance secreted from the ventricles in response to heart failure. You can actually measure the progression of heart failure using the B.N.P. marker. I immediately went to the lab for that test, and, sure enough, it was elevated. I now had a working diagnosis and could apply my knowledge in natural medicine.

Amazingly, none of these helpful articles were in the oncology (cancer) literature; they were only available in the cardiology literature. So, I printed the abstracts and sent them to all of the doctors I had worked with, thanking them for their excellent care and providing the information “for the next guy.”

Within ten days of starting my natural protocol, I was 75% better. However, I still would become extremely tired in the afternoon. I was forced to take a nap, because I simply could not go on without one. That’s where the exciting breakthrough I want to share with you comes in.

For years, I had been treating heart failure with CoQ10, as well as a variety of other supplements, including Cardiotrophin PMG (which contains micro-peptides that repair the heart tissue) and potassium/magnesium aspartate (which regulates the heart rhythm). CoQ10 is the enzyme that allows your muscles to use oxygen to produce energy in your mitochondria. I have personally taken 600 mg of CoQ10 for years, because I have pre-existing mitochondrial damage.

Although much of the literature recommends the reduced form of CoQ10 (ubiquinol), I have never found a large enough difference between it and ubiquinone to justify the increased cost. So, I utilize ubiquinone in my practice and monitor tissue edema to establish dosage. One of the functions of CoQ10 is to strengthen your heart muscle, thus reducing extracellular fluid accumulation and taking the load off of your heart.

Time for a slight digression into cellular metabolism; let me explain what mitochondria actually are. All of our cells contain them; they are the organelles that contain the electron transport chain, which converts the oxygen we breathe and the food we eat into adenosine triphosphate (ATP), or cellular gasoline. One study revealed that muscle tissue of a 90-year-old man contained mitochondria that were 95% damaged, while the mitochondria of a 5-year-old showed almost no damage. (Voet D, Voet JG, Pratt CW. “Fundamentals of Biochemistry: Life at the Molecular Level.” 2nd ed. New Jersey: John Wiley and Sons, Inc.; 2006:547.)

Over the years of my practice, I have assiduously searched for a supplement that would repair my mitochondria and reverse the effects of cellular aging. Nothing I tried was effective; and, unfortunately, CoQ10 has no effect on repairing your mitochondria or increasing their numbers; it can only work with what’s currently there.

Then, along came the research on pyrroloquinoline quinone; let’s call it PQQ, since no one can pronounce it. PQQ actually triggers your mitochondria to replicate, increasing the numbers of them in your cells. The effect is rejuvenating. Imagine having the energy and strength you had when you were young, and you had a full complement of mitochondria in all of your cells!

Researchers at the University of California at Davis are doing pioneering work in the study of PQQ. Their work shows a clear correlation between PQQ and the growth of new mitochondria. One of their studies was published in the Journal of Nutrition. In the study they fed mice a diet supplemented with PQQ; the mice grew a staggering number of new mitochondria in just 8 weeks. Here’s the graph of their findings:

PQQ

Stites, T. et al. “Pyrroloquinoline Quinone Modulates Mitochondrial Quantity and Function in Mice.” J. Nutr.February 2006 vol. 136 no. 2 390-396.

And, there’s even more good news. PQQ also stimulates the natural production of nerve growth factor, a substance that triggers the growth of new brain cells.

It also relieves the stress on your brain cells called excitotoxicity. This is the overstimulation of our brain cells that causes senility and loss of memory as we get older. Essentially, it returns our brains to a younger state. (Murase K, Hattori A, Kohno M, Hayashi K. “Stimulation of nerve growth factor synthesis/secretion in mouse astroglial cells by coenzymes.” Biochem Mol Biol Int. 1993 Jul;30(4):615-21 and Hara H, Hiramatsu H, Adachi T. “Pyrroloquinoline quinone is a potent neuroprotective nutrient against 6-hydroxydopamine- induced neurotoxicity.” Neurochem Res. 2007 Mar;32(3):489-95) I don’t know about you, but that was something I felt I needed desperately!

Furthermore, PQQ also keeps the mitochondria in your heart young. This is extremely important because mitochondria are fragile; they are extremely susceptible to toxic damage. So PQQ’s role as a protector of mitochondrial DNA is just as important as its ability to generate new ones. (Baggio E, Gandini R, Plancher AC, Passeri M, Carmosino G. “Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in

heart….” Mol Aspects Med. 1994;15 Suppl:s287-94 and Singh R, Wander G, Rastogi A, Shukla P, Mittal A, Sharma J, Mehrotra S, Kapoor R, Chopra R. “Randomized, double-blind placebo- controlled trial of coenzyme Q10 in patients …” Cardiovasc Drugs Ther.1998;12(4):347-53)

Within just a couple of weeks of taking PQQ at a dose of 20 mg daily, I noticed an immediate improvement in my energy. I no longer required a nap to continue functioning with my afternoon patients. I have now been taking it for more than 6 months, and I am now back to working 10-hour days, when necessary. I still get tired, but it is a healthy tired, which I bounce back from easily. I am truly getting my life back.

If you have problems with energy, thinking or stamina, I strongly recommend that you begin taking CoQ10 and MitoPQQ (that’s the brand name) daily. Please call me to order; I promise you will be amazed by the results over the period of just a few short weeks.

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Entry filed under: Heart Health.

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